VThunter
a database for single-cell screening of virus target cells in animal kingdom
...
Rat

Scientific Name: Rattus norvegicus

Taxonomy: Cellular organisms-> Eukaryota-> Opisthokonta-> Metazoa-> Eumetazoa-> Bilateria-> Deuterostomia-> Chordata-> Craniata-> Vertebrata-> Gnathostomata-> Teleostomi-> Euteleostomi-> Sarcopterygii-> Dipnotetrapodomorpha-> Tetrapoda-> Amniota-> Mammalia-> Theria-> Eutheria-> Boreoeutheria-> Euarchontoglires-> Glires-> Rodentia-> Myomorpha-> Muroidea-> Muridae-> Murinae

...
Hepacivirus C

Family: Flaviviridae

Receptor: CLEC4M

Receptor CLEC4M information

Summary: This gene encodes a C-type lectin that functions in cell adhesion and pathogen recognition. This receptor recognizes a wide range of evolutionarily divergent pathogens with a large impact on public health, including tuberculosis mycobacteria, and viruses including Ebola, hepatitis C, HIV-1, influenza A, West Nile virus and the SARS-CoV acute respiratory syndrome coronavirus. The protein is organized into four distinct domains: a C-terminal carbohydrate recognition domain, a flexible tandem-repeat neck domain of variable length, a transmembrane region and an N-terminal cytoplasmic domain involved in internalization. This gene is closely related in terms of both sequence and function to a neighboring gene, CD209 (Gene ID: 30835), also known as DC-SIGN. The two genes differ in viral recognition and expression patterns, with this gene showing high expression in endothelial cells of the liver, lymph node and placenta. Polymorphisms in the tandem repeat neck domain are associated with resistance to SARS infection. [provided by RefSeq, May 2020] [NCBI]  [Proteinatlas]

Data Source

Data set information

Project Date Technology Tissue Condition Cell PMID/DOI
Vthunter_1001 2019.12 10X Genomics Lung Normal 5029 Link
Vthunter_1002 2019.12 10X Genomics Lung Normal 5924 Link
Vthunter_110073 2019.12 MARS-seq TotalBrain Normal 2304 Link
Featureplot of receptors

Featureplot of receptors

mRNA expression of CLEC4M in human tissues   [NCBI]

Expression: Biased expression in liver (RPKM 15.4), lymph node (RPKM 9.8) and 3 other tissues?

Protein expression of CLEC4M in human tissues   [Proteinatlas]